Cardiovascular Diseases and Cardiac Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. the Mayo Cardiac Sarcoid Registry

   Rochester, Minn., Jacksonville, Fla.

   Aims, purpose, or objectives:

   1. Develop a retrospective registry of patients with cardiac sarcoidosis
   2. Develop a prospective registry of patients with cardiac sarcoidosis
   3. Understand the natural history of cardiac sarcoidosis through evaluation of outcomes of patients in the registry
   4. Determine risk factors for sarcoid involvement of the heart
   5. Evaluate outcomes of patients both treated and untreated with cardiac sarcoidosis
   6. Understand the complications of untreated and treated cardiac sarcoidosis

    

2. (FMD Impact Registry) Fibromuscular Dysplasia Findings and Outcomes

   Rochester, Minn.

   To describe the clinical, laboratory, pathologic, imaging findings, therapy and outcomes in all patients with Fibromuscular Dysplasia (FMD) and/or segmental arterial mediolysis evaluated at Mayo Clinic retrospectively (back to 01/01/1990) and prospectively (starting 04/13/2016).

3. A Study to Evaluate Sleep for Stroke Management and Recovery

   Rochester, Minn.

   The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.

4. A Study to Evaluate Perceptions of Midline Sternotomy Scar in Children and Young Adults

   Rochester, Minn.

   The purpose of this study is to evaluate how children and young adults perceive their midline sternotomy scars (in terms of appearance, associated symptoms, consciousness, satisfaction with appearance/symptoms, and impact on quality of life)? 

5. Study to Determine the Accuracy of a New Venous Air Plethysmograph in People with Normal, Incompetent, and Obstructed Venous Hemodynamics.

   Rochester, Minn.

   The purpose of this study is to determine the accuracy (sensitivity, specificity, negative predictive value, positive predictive value) of a new venous air plethysmograph in people with normal, incompetent, and obstructed venous hemodynamics.

6. A Study to Assess the Current FDA-approved AliveCor Kardia Device to Measure the QT/QTc in Patients Presenting to the Genetic Heart Rhythm Clinic

   Rochester, Minn.

   The purpose of this study is to assess the feasibility of using the current FDA-approved AliveCor Kardia device and their AliveCor Tripod device (FDA Approval pending) to measure the QT/QTc in patients presenting to the Genetic Heart Rhythm Clinic.

7. A Repository of Atria Tissue for the Investigation of Atrial Pathophysiology in Patients with Atrial Fibrillation

   Rochester, Minn.

   The purpose of this study is to collect surgically removed atrial tissue for genetic, pathologic, metabolic, and molecular studies in patients with or without a history of atrial fibrillation.

8. Post Approval Study for Treatment of Drug-resistant Adult Primary FSGS Using the LIPOSORBER® LA-15 System

   Rochester, Minn., Jacksonville, Fla.

   The purpose of this study is to evaluate the probable benefit and safety of the LIPOSORBER® LA-15 System for the treatment of adult and pediatric patients with nephrotic syndrome associated with primary focal segmental glomerulosclerosis, when the standard treatment options, including corticosteroid and/or calcineurin inhibitors treatments, have been unsuccessful or not well tolerated, and the patient has a GFR ≥ 45 ml/min/1.73m2, or the patient is post renal transplantation. Treatment for FSGS is considered unsuccessful if the patient is unresponsive to standard therapy (e.g., at least 8 weeks of corticosteroids) and fails to achieve complete or partial remission. A standard treatment is considered not well tolerated if the patient experiences severe side effects without providing an acceptable level of clinical benefit.

    

9. A Study to Establish a Registry for the Pulmonary Hypertension Association

   Jacksonville, Fla.

   The objectives of this study are to measure and improve quality of care (including assessing differences in adherence to evidence-based guidelines and establishing benchmarks for health outcomes); determine the clinical effectiveness, comparative effectiveness, and cost effectiveness of treatment approaches; understand risk factors for outcomes and regional/center differences; and facilitate funded clinical trials of new therapies and collaboration with the PAH community at large, including providers, patients, and their caregivers.

10. A Study to Assess Measurements in Cardiomyopathy Patients Using Software for Multi-level Reconstruction of Three Dimensional Transesophageal Echocardiography (TEE) or Transthoracic Echocardiography (TTE) Images

    Rochester, Minn.

    The purpose of this study is to utilize three dimensional (3D) transesophageal echocardiography (TEE) or 3D transthoracic echocardiography (TTE) to measure various mitral chordal, annular, and leaflet measurements and LV size to better understand the mechanism of regurgitation in patients with FMR.